A phase I, randomized, observer-blinded, single and multiple ascending-dose study to investigate the safety, pharmacokinetics, and immunogenicity of BITS7201A, a bispecific antibody targeting IL-13 and IL-17, in healthy volunteers | BMC Pulmonary
Safety, pharmacokinetics, and pharmacodynamics of pegozafermin in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo- controlled, phase 1b/2a multiple-ascending-dose study - The Lancet Gastroenterology & Hepatology
Single Ascending Dose & Multiple Ascending Dose
Two Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single-Ascending- Dose Studies To Investigate the Safety, Tolerability, and Pharmacokinetics of an Anti-Influenza A Virus Monoclonal Antibody, MHAA4549A, in Healthy Volunteers | Antimicrobial ...
Multiple-Ascending-Dose Phase 1 Clinical Study of the Safety, Tolerability, and Pharmacokinetics of CRS3123, a Narrow-Spectrum Agent with Minimal Disruption of Normal Gut Microbiota | Antimicrobial Agents and Chemotherapy
Study design: (A) single ascending dose; (B) multiple ascending dose. | Download Scientific Diagram
Pharmacokinetics of ASP4345 from Single Ascending-Dose and Multiple Ascending-Dose Phase I Studies | SpringerLink
A Randomized, Double-Blind, Placebo-Controlled, First-Time-in-Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of GSK3389404 in Healthy Subjects. - Abstract - Europe PMC
CR TidBit – Single Ascending Dose to Multiple Ascending Dose. | AuroBlog | Clinical Research Blog | Aurous HealthCare CRO, India
Study flow chart showing a multiple ascending dose design. | Download Scientific Diagram
Phase I: Overview
The phases of preclinical and clinical trials
CR Tidbit – SAD MAD Studies | AuroBlog | Clinical Research Blog | Aurous HealthCare CRO, India
A First‐in‐Human Phase 1 Randomized Single and Multiple Ascending Dose Study of RPh201 in Healthy Volunteers - Hazan - 2020 - Clinical Pharmacology in Drug Development - Wiley Online Library
On Biostatistics and Clinical Trials: SAD and MAD: Single Ascending Dose and Multiple Ascending Dose first-in-human studies
STATISTICAL ANALYSIS PLAN Protocol PQ-010-001 PHASE 1B, RANDOMIZED, DOUBLE-BLIND, PLACEBO- CONTROLLED, DOSE ESCALATION STUDY TO
Study design with overlapping SAD-MAD cohorts, where treatment periods... | Download Scientific Diagram
Study design. The study included single and multiple ascending... | Download Scientific Diagram
Phases of clinical trial 11.9.14
Schematic of the ECG timepoints and meals in the single-ascending dose... | Download Scientific Diagram
A Flow-chart of the single-ascending-dose (SAD) and... | Download Scientific Diagram
